Thesis (Ph.D.) - University of East Anglia, School of Biological Sciences, 1976.
Michael George Rhodes has written: 'Inhibition of the Na plus, K plus - stimulated ATPase by organotin compounds' Asked in Software Engineering, C++ . Neurologic sequelae of tributyltin intoxication in rats. ) studies focused on the possible link between the Na,K-ATPase inhibition and hydromineral dysfunctions, Organotin compounds. The inactivation of Ca 2+-ATPase by organotin compounds causes the observed sustained increase in cytosolic calcium, consequently giving rise to a series of Ca 2+-dependent toxic mechanisms of action such as cytoskeleton disassembly, calmodulin inhibition and apoptosis (Cima et al., , Cima and Ballarin, ).Cited by: A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.
The enzyme activity was assayed in triplicate in a reaction medium (1 mL) containing mg mitochondrial protein, 75 mM ethanolamine–HCl buffer, pH , mM MgCl 2 plus mM Na 2 ATP. After 5 min preincubation at selected temperatures in the range 12–37 °C, with 2–3° intervals, the reaction, carried out at the same temperature of Cited by: 2. The luminescence of the chiral thioxanthones incubations relative to that of the Na 3 VO 4-treated reactions reflects the effect, if any, of that compounds on P-gp ATPase activity (i.e., a decrease in luminescence reflects a stimulated P-gp ATPase activity). Three independent experiments were performed in triplicate for this assay and the Cited by: 4. Models for the Biosynthesis of an Acetylenic Bond. During the early s, two models put forward for the biosynthesis of polyacetylenes, the oxidative dehydrogenation (desaturation) mechanism and a decarboxylative enol elimination mechanism, used divergent approaches to the formation of the second π-bond (Fig. 2).The desaturation model, supported by the landmark . *Bloomquist JR, Adams PM, Soderlund DM. Inhibition of gamma-aminobutyric acid- stimulated chloride flux in mouse brain vesicles by polychlorocycloalkane and pyrethroid insecticides. Neurotoxicology 7(3) *Bolger R, Wiese TE, Ervin K, et al. Rapid screening of environmental chemicals for estrogen receptor binding capacity.
Abstract Book Members Horacio Asprea SAyDS Buenos Aires, Argentina The Society of Environmental Toxicology and Chemistry (SETAC), with offices in North America and Europe, is a nonprofit, professional society established to provide a forum for individuals and institutions engaged in the study of environmental problems, management and. Measurement of organotin = compounds These methods, which are summarized in Table 2, have been applied initially to water and later to sediment and biota. They must be sufficiently sensitive and specific to allow monitoring of ng/litre levels, and they need to be able to distinguish between different forms of organic tin derivatives present in. From A Textbook of Modern Toxicology, 3rd ed., ed. E. Hodgson. New York: Wiley, the formation of a colored insoluble product of an enzymatic reaction, the enzyme, such as alkaline phosphatase or horseradish peroxidase, being covalently linked to the secondary antibody. PROJECT TEAM FOR DEVELOPMENT OF Air Quality Criteria for Lead Dr. David E. Weil, Project Manager and Coordinator for Chapters 1 Volume I and IV, and Addendum Environmental Criteria and Assessment Office (MD) U.S. Environmental Protection Agency Research Triangle Park, N.C. Dr. J. Michael Davis Coordinator for Chapters 9.